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KMID : 0942820080070010033
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Journal of Korean Brain Tumor Society
2008 Volume.7 No. 1 p.33 ~ p.37
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Clinical Analysis of Hemangioblastoma
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Lee Seung-Hwan
Park Bong-Jin
Kim Tae-Sung
Lim Young-Jin
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Abstract
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Objective: To find the most important factors of the clinical outcomes of the intracranial hemangioblastomas, we analyzed all the patients admitted to our hospital from 1986 to 2005 with hemangioblastoma.
Methods: This study included all the patients with histologically verified hemangioblastoma in our hospital over a period of 20 years. The medical, radiological, surgical records from these patients were reviewed retrospectively.
Results: There was a total 37 patients(16 males and 21 females). 32 patients(86.5%) harbored sporadic hemangioblastoma. 5 patients(13.5%) had von Hippel-Lindau syndrome. 30 out of 37 patients underwent total removal surgery were more likey to have good tumor control than 7 patients whose tumor were subtotally or partially removed required adjuvant therapy. Among subtotally removed patients, 4 patients were treated with radiosurgery and 3 patients with conventional radiotheraphy. Three of subtotally removed patients underwent 2nd surgery for recurred tumor, and 1 patient expired due to radiation induced glioblastoma multiforme.
Conclusion: In the treatment for intracranial hemangioblastoma, surgically total removal was treatment of choice. If tumor was subtotally removed, radiosurgery for remnant tumor will be adequate for adjuvant therapy.
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KEYWORD
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Hemangioblastoma, von Hippel-Lindau disease
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